Upper Limits of Normal for Serum Alanine Aminotransferase Levels in Chinese Han Population
نویسندگان
چکیده
منابع مشابه
Upper Limits of Normal for Serum Alanine Aminotransferase Levels in Chinese Han Population
BACKGROUND AND OBJECTIVES Serum alanine aminotransferase (ALT) activity is the most common tool for the assessment of liver diseases. However, it is not clear whether the current normal ALT range really discriminate patients with or without liver diseases. The present study was to establish a new normal range of ALT and examine its ability to identify patients with hepatitis B or nonalcoholic f...
متن کاملUpper limit of normal for alanine aminotransferase: quo vadis?
Several studies suggest that a substantial number of patients with normal serum alanine aminotransferase (ALT) levels, defined by current thresholds, have ongoing hepatic necro-inflammation and fibrosis, and are at risk of liver disease progression. A major problem lies in the definition of normality. The current upper limit of normal (ULN) for ALT was established in the 1980s when reference po...
متن کاملRe-evaluation of serum alanine aminotransferase upper normal limit and its modulating factors in a large-scale population study.
BACKGROUND The upper normal limit (ULN) of serum alanine-aminotrasferase (ALT) normal range was recently challenged, because patients diagnosed with liver diseases may have 'normal' or near-'normal' ALT levels, and because possible modulators are often ignored in determining normal range. AIM To estimate the ULN for serum ALT and to identify factors modulating it. SUBJECTS AND METHODS We re...
متن کاملAssociation of Serum Alanine Aminotransferase Levels with Cardiometabolic Risk Factors in Normal-Weight and Overweight Children
OBJECTIVE This study aimed to determine the prevalence of increased alanine aminotransferase (ALT), defined by a gender-specific cutoff value, among normal weight and overweight children; and to assess the relationship of increasing ALT levels with cardiometabolic risk factors. METHODS This cross-sectional study was conducted among school students, aged 6-18 years in Isfahan, Iran. Based on t...
متن کاملSerum alanine aminotransferase/aspartate aminotransferase ratio is one of the best markers of insulin resistance in the Chinese population
BACKGROUND The alanine aminotransferase (ALT)/aspartate aminotransferase (AST) ratio is reportedly associated with insulin resistance (IR). However, few studies have explored the relationship between the ALT/AST ratio and IR in the Chinese population. Here, we aimed to explore whether the ALT/AST ratio is associated and, if so, to what extent, with IR in the Chinese population as categorized by...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: PLoS ONE
سال: 2012
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0043736